The one-hour debate will be broadcast at 8 a.m. on WLNY 10/55 and at 1 p.m. on both CBS 2 and WCBS-Newsradio 880.
The debate will also be streamed on CBS New York.com at 1 p.m.
The debate will be recorded on Thursday.
CBS 2 News anchor Kristine Johnson will serve as the debate's moderator.
CBS 2 chief political correspondent Marcia Kramer and WCBS-Newsradio 880 Long Island bureau chief Mike Xirinachs will serve as panelists.
The Fair Media Council is partnering with CBS to put on the event.
Mangano is fighting for a second term as county executive, while Suozzi is trying to win back the job he held for two terms before Mangano unseated him in 2009.
Mangano held a lead in the last survey.